Abstract: Based on the daily precipitation data of 106 rainfall stations in Taihu Basin from 1961 to 2015, MannKendall trend test method is used to analysis trend of annual precipitation in the Basin and its 7 water conservancy districts, and sequential clustering method is used to study the time mutation of precipitation. The results show that the precipitation indicators in the Taihu Lake Basin and its sub-regions are on the rise, and the rising trend is more obvious in the eastern part of the basin, and the time mutation range of precipitation in the basin and its subregions is basically the same.